Dangers of non sedating antihistamines pubmed

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The pharmacology and therapeutic use of H1 and H2 antihistamines.

Cold, cough, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; tentative final monograph for OTC antihistamine drug products.

Because geriatric patients frequently have decreased renal function, evaluate renal function prior to initiation and subsequently thereafter in this age group; adjust dosage if renal impairment exists or develops. Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action.

(See Renal Impairment under Dosage and Administration.) Children 2–5 years of age receiving oral solution: Diarrhea, epistaxis, pharyngitis, flu-like symptoms, fatigue, stomatitis, tooth disorder, earache, viral infection, rash.

† Use is not currently included in the labeling approved by the US Food and Drug Administration. Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever. Dear doctor letter regarding mechanical upper GI obstruction with Claritin-D 24 Hour tablets. The antiallergic effects of antihistamines (H1-receptor antagonists). Loratadine: a nonsedating antihistamine with once-daily dosing.

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